How do the instructions to make proteins work? Preview CT-STEM

A closer look at DNA synthesis - 2

Let’s use that test tube model to see how DNA gets made.

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Questions

Please answer the questions below.

Question 5.1

What patterns do you see after DNA is replicated?

Question 5.2

Record the percentages of each nucleotide (A, T, G, C) in the table below once the new strand of DNA has been fully synthesized (move the “ticks” slider to the right to speed it up and adjust the deoxyribonucleotide number, if necessary). Carry out this process 2 times to fill out the table.

Question 5.3

What do you notice about the percentages in each trial? (look across more than just one letter in each trial)

Question 5.4

SAQ: This relationship is called “Chargaff’s rule” after the scientist who discovered it in the late 1940s. It helped other scientists figure out the structure of DNA and how DNA can contain the information necessary to make copies of itself. Use the information from the last few questions and the model to write an algorithm for DNA polymerase to function (the steps DNA polymerase needs to follow to replicate DNA).

Notes

These notes will appear on every page in this lesson so feel free to put anything here you'd like to keep track of.